DNA Origami Nanobots vs. Cancer – It’s about the Creativity of Bioengineering

See on Scoop.itThings I Grab (Here and There): THgsIGrbHT

Shawn Douglas has big ideas to help fight cancer. His two roadblocks to a cure are that cancer drugs lack specificity and the cancer cells develop resistance to treatment over time. His radical solution in this Solve for X talk is to develop a new class of drugs from nanoscale devices. Inspiration comes in part from the way that penicillin fights infection. Penicillin can eat the harmful bacteria in an infection without doing harm to the host body.

 

Cancer cells, however, are close in makeup to the healthy cells that they have replaced and harder to individually target. Douglas uses animations and a gruesome graphic of a melanoma patient to explain how cancer cells can develop resistance to medicine and return stronger than original levels. To solve the specificity problem Douglas proposes a targeted delivery method that can differentiate between healthy cells and cancer cells. To solve the resistance problem he proposes combining different treatment methods to ensure all the different types of cancer cells are removed.

 

The solution to fit both sets of problems and constraints is nanoscale devices. In the lab Douglas and his team use a method codenamed DNA origami where hundreds of short DNA strands combine to create custom shapes with nanoscale precision. The devices act as a shell that delivers payload atoms to the exact cell that is targeted. Top and bottom halves are held together with strands and when signaled can open up like a clamshell, delivering the drug.

 

Extensive testing has been done in the lab to obtain a proof-of-concept level of confidence. Goals for the future include much more testing on live subjects, a method of mass production, finding new applications for nanobot delivery, and lots of new scientists. Douglas ends the talk discussing his BioMod student design competition and reminding us that bringing up the next generation of nanoscale device engineers is his most important project.

 

http://tinyurl.com/l4nel5w

See on www.engineering.com

Advertisements

About plerudulier

Primarily interested in interacting and engaging with people about issues related to profession but also charity, environment, ... you get the idea.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

w

Connecting to %s

demontvalon1 le blog

Blog de Dominique de Montvalon, journaliste-éditorialiste politique

Invention - Europe

Le portail des inventeurs, des inventions et des innovations en Europe, propose des services gratuits pour aider les inventeurs à développer leurs inventions sur le Web. Ce site communautaire pour les inventeurs existe depuis avril 2001. Invention - Europe est le N°1 des sites francophones, sur le thème de l'invention. Fondé par Peter TEMEY, il est géré par l'association "Club Invention - Europe". Le site Invention - Europe est indépendant et refuse toute publicité payante.

BINAKUKO

Biso Na Bino ! Tous ensemble !

Les mille et une facettes

Sports, droit, médias, musiques, cinéma et remise en forme, voici le blog que tu dois voir !

Simplify Tasks

Want to learn the simple way?

Mademoiselle Maeve

Mademoiselle Maeve lit des livres

Bill Wirtz

Freelance journalist - Writer for a free society

Le magazine en ligne de la Fondation littéraire Fleur de Lys

Nouvelles, chroniques, dossiers, revue de presse,...

Urban Food Futures

The first online science magazine dedicated to sustainable urban food systems

Média des innovations agricoles

Partager les agricultures de demain

NicoChagny.net

Blog de veille de Nicolas CHAGNY /// DGA Data&Digital Services @ Makheia /// Président @ Internet Society France

Télégraphe 78

Télégraphe 78 : Pour mieux connaître la Vie Numérique du Sud-Yvelines !

Macademise

How to do your research on a mac.

Miss Marks Blogs

Teaching outside of my comfort zone

Java and Junket

Conversations about coffee, travel, and getting the most out of life

Paul's Project Server and Project Online Blog

Microsoft Project Server and Project Online (PPM)

Steve Goodyear

The SharePoint Whisperer's Notes & Ideas

%d bloggers like this: